IconAcute Renal Failure in Newborn (ARF)

ARF in newborn:

  • Incidence:8-23% in NICU
  • Presents in first 24- 48 hours of life
  • Most common cause- hypoperfusion Hypoxia

    • Causes of ARF

    • Pre renal
      • Hypotension/ shock
      • CCF
      • Hydrops
      • Dehydration 
    • Renal
      • Glomerular
      • Tubulointerstitial
      • Vascular
    • Post renal
      • Pu valves
      • Stricture
      • Diverticulum, ureterocele
      • Single kidney with obstruction

    Acute Tubular Necrosis (ATN):

  • Hypoperfusion
  • Anoxia- hypoxia
  • Drugs aminoglycosides:NSAIDS, ACE Inhibitors, Contrast media
  • Sepsis

    • Investigations:

  • CBC
  • BUN
  • S.Creatinine
  • Bicarconates(HCO3)

    • Management :

  • Daily weight
  • Strict input and output chart
  • Avoid nephrotoxic drugs
  • Dose adjustment for Renal Failure
  • Fluid and Electrolyte balance

    • Indications for Peritoneal Dialysis:

  • Hyperkalemia Increased serum pottasium levels
  • Refractory acidosis
  • Fluid overload

    • Diagnosis

  • Weight
  • Urine:U.Osmolality, U. Na, U.Creatinine,Fena
  • Ulrasound of Kidney Ureter and Bladder


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    email: drmehtaks@kidskidneycare.in | drmehtaks@yahoo.co.in

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